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Connecting the Dots

  • Jyothi Arikkath
    Affiliations
    Department of Developmental Neuroscience, Munroe-Meyer Institute for Genetics and Rehabilitation
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  • Károly Mirnics
    Correspondence
    Address correspondence to: Károly Mirnics, M.D., Ph.D., University of Nebraska Medical Center, Munroe-Meyer Institute for Genetics and Rehabilitation, 444 South 44th Street, Room 2005 985450, Omaha, NE 68198; .
    Affiliations
    Department of Developmental Neuroscience, Munroe-Meyer Institute for Genetics and Rehabilitation

    Department of Psychiatry, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska

    Department of Biochemistry and Molecular Biology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska
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      One of the most widely observed and robust findings in schizophrenia (SCZ) is altered connectivity between brain regions involved in cognition and emotion. In this issue, Romme et al. (
      • Romme I.A.C.
      • de Reus M.A.
      • Ophoff R.A.
      • Kahn R.S.
      • van den Heuvel M.P.
      Connectome disconnectivity and cortical gene expression in patients with schizophrenia.
      ) provide a new look at the interaction between genes playing a role in SCZ pathophysiology and cortical disconnectivity observed in patients.
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