Opioids such as morphine, oxycodone, and fentanyl are widely used as effective analgesics
for treating acute and chronic pain. Although appropriate use of opioid analgesics
is an essential part of effective pain management, abuse and dependence on opioids
pose a threat to health and have a devastating social and economic impact on families,
communities, and nations. In a systematic analysis of the epidemiology of drug dependence
with “global burden of disease,” Degenhardt et al. (
1
) identified opioid dependsence as the largest contributor to the direct burden of
disease among all illicit drugs.To read this article in full you will need to make a payment
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References
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Article info
Publication history
Accepted:
April 22,
2014
Received:
April 17,
2014
Identification
Copyright
© 2014 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
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- Genome-Wide Association Study of Opioid Dependence: Multiple Associations Mapped to Calcium and Potassium PathwaysBiological PsychiatryVol. 76Issue 1
