Generalized anxiety disorder (GAD) is a mental illness with an overall prevalence of 4% to 7% (
1). It ts characterized by a subjective sensation of uncontrollable worry and multiple physiological symptoms such as sleep disturbances, muscle tension, and difficulties concentrating. Current treatment strategies are based on both psychological and pharmacologic therapies, although treatment-resistance and low adherence due to adverse effects are some issues that compromise optimal treatment. In fact, only some patients fully respond after an adequate antidepressant drug trial (
- Kessler R.C.
- Chiu W.T.
- Demler O.
- et al.
Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication.
Arch Gen Psychiatry. 2005; 62: 617-627
2). Additional research to improve GAD treatment is therefore neeeded.
- Craske M.G.
- Edlund M.J.
- Sullivan G.
- Roy-Byrne P.P.
- Sherbourne C.D.
- Bystritsky A.
- Stein M.B.
Perceived unmet need for mental health and barriers to among care patients with panic disorder.
Psychiatr Serv. 2005; 56: 988-994
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- Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication.Arch Gen Psychiatry. 2005; 62: 617-627
- Perceived unmet need for mental health and barriers to among care patients with panic disorder.Psychiatr Serv. 2005; 56: 988-994
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Published online: August 19, 2013
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