Generalized anxiety disorder (GAD) is a mental illness with an overall prevalence
of 4% to 7% (
1
). It ts characterized by a subjective sensation of uncontrollable worry and multiple
physiological symptoms such as sleep disturbances, muscle tension, and difficulties
concentrating. Current treatment strategies are based on both psychological and pharmacologic
therapies, although treatment-resistance and low adherence due to adverse effects
are some issues that compromise optimal treatment. In fact, only some patients fully
respond after an adequate antidepressant drug trial (
2
). Additional research to improve GAD treatment is therefore neeeded.To read this article in full you will need to make a payment
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Article info
Publication history
Published online: August 19, 2013
Identification
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© 2014 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
