One of the pivotal diagnostic distinctions in psychiatry is between bipolar disorder
and schizophrenia. Manic depressive psychosis was distinguished from psychosis in
general in the 19th century and, following Kraepelin's work in the early 20th century,
schizophrenia was differentiated in terms of its phenomenology and natural history.
Although this clinical compartmentalization of psychosis has been useful and enduring,
there is increasing evidence that under the hood of the classically different phenotypes
there may be more in common between bipolar disorder and schizophrenia than a strict
Kraepelinian dichotomy would predict (
1
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Article info
Publication history
Accepted:
March 21,
2012
Received:
March 19,
2012
Identification
Copyright
© 2012 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
