Commentary| Volume 71, ISSUE 7, P570-571, April 01, 2012

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Euthymia, Depression, and Mania: What Do We Know About the Switch?

      The holy grail for research in bipolar disorder (BD) is the mechanism that underlies the switch to acute manic and depressive episodes. Armed with knowledge of the switch, researchers could more effectively prevent and treat episodes of this disorder. However, the switch mechanism has been elusive and the quest continues.
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