This issue of Biological Psychiatry is entitled “Medical Consequences and Contributions to Depression” and includes several
reports that describe relationships between depression or symptoms of depressed mood
and somatic changes outside the central nervous system. These reports add to a body
of research suggesting that depression adversely affects overall health outcomes in
a variety of ways and, conversely, that systemic illness and chronic stress can have
negative consequences and long-term sequelae in the brain, including symptoms of depression.
Together they speak to the complex interrelationship between depression and overall
health. Additionally, they raise important questions about how we understand depression
as a medical illness and about the role of studying the body outside the central nervous
system as part of a research strategy in depression and other brain disorders.
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Article info
Publication history
Accepted:
June 2,
2009
Received:
June 1,
2009
Identification
Copyright
© 2009 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
