We thank Thombs and colleagues for their close reading of our article, which has identified
an issue related to the inclusion and coding of “dummy” variables for certain effects.
By prompting a reexamination of our data, their letter has helped to clarify further
the role of post–acute coronary syndrome (ACS) depression.
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Published online: March 23, 2009
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© 2009 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
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- Timing May Be Important, but Methodology Is Everything: A Commentary on Parker et al.Biological PsychiatryVol. 66Issue 3
- PreviewParker et al. (1) argued that in predicting cardiac readmission or death following an acute coronary syndrome (ACS), “Timing is everything.” On the basis of multivariate logistic regression, they reported that patients who developed a depressive episode in the month following an ACS admission, whether incident or recurrent, had on average 7 times the odds (95% confidence interval [CI] = 2.21–22.17) for ACS readmission or cardiac mortality compared with patients with no depression before or after the ACS.
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