With the widespread availability of functional magnetic resonance imaging (fMRI),
there has been rapid progress in identifying neural correlates of cognition and emotion
in the human brain. In conjunction with basic research studies, fMRI has been increasingly
applied in clinical disorders, making it a central research tool in human psychopathology,
psychopharmacology, and genetics. In the present article, we discuss a number of conceptual
and methodological challenges that confront the implementation of fMRI in clinical
and translational research, and we offer a set of recommendations intended to enhance
the interpretability and reproducibility of results in clinical fMRI.
Key Words
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Article info
Publication history
Published online: August 22, 2008
Accepted:
June 12,
2008
Received in revised form:
June 9,
2008
Received:
April 24,
2008
Identification
Copyright
© 2008 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
