Background
Schizophrenia is a neurocognitive disorder with a wide range of cognitive and sensory
impairments. Early visual processing has been shown to be especially impaired. This
article investigates the integrity of binocular depth perception (stereopsis) in schizophrenia.
Methods
Seventeen schizophrenia patients and 19 healthy control subjects were compared on
the Graded Circles Stereo Test. Results of stereoacuity were compared between patients
and control subjects using t test.
Results
Schizophrenia patients demonstrated significantly (p = .006) reduced stereoacuity (mean = 142 arcseconds) versus control subjects (mean
= 55 arcseconds). At the normative level for adults, patients performed below chance.
Conclusions
These findings demonstrate an impairment of binocular depth perception and further
confirm deficits of early visual processing in schizophrenia. Findings are discussed
in context of magnocellular/dorsal stream processing with implications for visual
processing and cognitive deficits.
Key Words
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References
- Human cortical activity correlates with stereoscopic depth perception.J Neurophysiol. 2001; 86: 2054-2068
- Dysfunction of early-stage visual processing in schizophrenia.Am J Psychiatry. 2001; 158: 1126-1133
- Early-stage visual processing and cortical amplification deficits in schizophrenia.Arch Gen Psychiatry. 2005; 62: 495-504
- Motor co-ordination deficits as predictors of schizophrenia among Finnish school children.Hum Psychopharmacol Clin Exp. 1999; 14: 491-497
- Motion perception in schizophrenia.Arch Gen Psychiatry. 1999; 56: 149-154
- Impaired visual object recognition and dorsal/ventral stream interaction in schizophrenia.Arch Gen Psychiatry. 2002; 59: 1011-1020
- Why two eyes are better than one: The two views of binocular vision.J Exp Psychol Hum Percept Perform. 1981; 7: 30-40
- Vernier threshold in patients with schizophrenia and in their unaffected siblings.Neuropsychology. 2004; 18: 537-542
- Psychophysical evidence for separate channels for the perception of form, color, movement, and depth.J Neurosci. 1987; 7: 3416-3468
- Depth perception in Alzheimer’s disease.Percept Mot Skills. 1996; 83: 987-995
- Stereopsis-processing regions in the human parieto-occipital cortex.Neuroreport. 2001; 12: 2259-2263
- Stereopsis after unilateral anterior temporal lobectomy.Brain. 1991; 114: 1323-1333
- Magnocellular and parvocellular contributions to backward masking dysfunction in schizophrenia.Schizophr Res. 2003; 64: 91-101
- Impairments in generation of early-stage transient visual evoked potentials to magno- and parvocellular-selective stimuli in schizophrenia.Clin Neurophysiol. 2005; 116: 2204-2215
- Stereoacuity norms in young children.Arch Ophthal. 1981; 99: 439-445
- Luminance flicker sensitivity in positive- and negative-symptom schizophrenia.Exp Brain Res. 2001; 138: 88-99
Article info
Publication history
Published online: August 30, 2006
Accepted:
March 28,
2006
Received in revised form:
March 23,
2006
Received:
June 29,
2005
Identification
Copyright
© 2006 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.