Background
Nine DSM-IV-TR criterion symptom domains are evaluated to diagnose major depressive
disorder (MDD). The Quick Inventory of Depressive Symptomatology (QIDS) provides an
efficient assessment of these domains and is available as a clinician rating (QIDS-C16), a self-report (QIDS-SR16), and in an automated, interactive voice response (IVR) (QIDS-IVR16) telephone system. This report compares the performance of these three versions of
the QIDS and the 17-item Hamilton Rating Scale for Depression (HRSD17).
Methods
Data were acquired at baseline and exit from the first treatment step (citalopram)
in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial. Outpatients
with nonpsychotic MDD who completed all four ratings within ±2 days were identified
from the first 1500 STAR*D subjects. Both item response theory and classical test
theory analyses were conducted.
Results
The three methods for obtaining QIDS data produced consistent findings regarding relationships
between the nine symptom domains and overall depression, demonstrating interchangeability
among the three methods. The HRSD17, while generally satisfactory, rarely utilized the full range of item scores, and
evidence suggested multidimensional measurement properties.
Conclusions
In nonpsychotic MDD outpatients without overt cognitive impairment, clinician assessment
of depression severity using either the QIDS-C16 or HRSD17 may be successfully replaced by either the self-report or IVR version of the QIDS.
Key Words
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Article info
Publication history
Published online: October 04, 2005
Accepted:
August 5,
2005
Received in revised form:
July 7,
2005
Received:
January 10,
2005
Identification
Copyright
© 2006 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
