Despite efficacious and widely available antidepressants and psychotherapeutic interventions,
the psychosocial and medical burden of depression is increasing. In fact, the World
Health Organization projects that depression will continue to be prevalent, and by
the year 2020, will remain a leading cause of disability, second only to cardiovascular
disease (
Michaud et al., 2001
). Although we do not know with certainty why rates and disability associated with
depression are increasing, it is likely that this mood disorder continues to be remarkably
under-recognized and under-treated. Depression frequently occurs in the context of
chronic medical illness, and it is only relatively recently that the research community
has turned its attention to the relationship between depression and chronic medical
conditions. However, there is much work yet to be done. The recently released
Institute of Medicine 2003
acknowledged depression as one of a number of chronic conditions that requires priority
action, but did not address the importance of comorbid depression and medical illness.To read this article in full you will need to make a payment
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© 2003 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.