Abstract
Transcranial magnetic stimulation is investigated as a new tool in the therapy of
depression and other psychiatric disorders. In almost all studies, the dorsolateral
prefrontal cortex (DLPFC) has been selected as the target site for stimulation. Usually
this region was determined by identifying the patient’s motor cortex, and from there
the coil was placed 5 cm rostrally. The aim of our study was to test the reliability
of this standard procedure. A neuronavigational system was used to relate the final
coil position after applying the standard procedure to the individual cortical anatomy.
In 7 of 22 subjects, the Brodman area 9 of the DLPFC was targeted correctly in this
manner. In 15 subjects, the center of the coil was found to be located more dorsally
(e.g., above the premotor cortex). The current method for locating the DLPFC is not
precise anatomically and may be improved by navigating procedures taking individual
anatomy into account.
Keywords
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Article Info
Publication History
Accepted:
March 27,
2001
Received in revised form:
March 22,
2001
Received:
January 8,
2001
Identification
Copyright
© 2001 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
