The articles in this issue of Biological Psychiatry are derived from oral presentations at a conference, “Depression in the 21st Century:
New Insight into Drug Development and Neurobiology,” held February 2–22, 2000 in Dana
Point, California. The speakers represented a range of clinical practitioners, pathologists,
and preclinical investigators, with strong focus on the neurobiology of mood disorders,
as well as a few basic scientists like myself who had a strong interest in the field
but little experience with directly relevant models. My comments here reflect a view
of biological psychiatry from the perspective of a generalist observing a fast moving
field, integrating basic observations in neurobiology with clinically defined problems.
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References
- Neuroimaging studies of mood disorders.Biol Psychiatry. 2000; 48: 813-828
- Neuronal plasticity and survival in mood disorder.Biol Psychiatry. 2000; 48: 732-739
- Imaging serotonergic neurotransmission in depression.Biol Psychiatry. 2000; 48: 801-812
- Regulation of hippocampal neurogenesis in adulthood.Biol Psychiatry. 2000; 48: 715-720
- Effects of early adverse experiences on brain structure and function.Biol Psychiatry. 2000; 48: 778-790
- Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers.Biol Psychiatry. 2000; 48: 740-754
- Regional metabolic effects of fluoxetine in major depression.Biol Psychiatry. 2000; 48: 830-843
- Effects of adverse experiences for brain structure and function.Biol Psychiatry. 2000; 48: 721-731
- Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells.Biol Psychiatry. 2000; 48: 766-777
- The possibility of neurotoxicity in the hippocampus in major depression.Biol Psychiatry. 2000; 48: 755-765
- 3D MRI studies of neuroanatomic changes in unipolar major depression.Biol Psychiatry. 2000; 48: 791-800
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© 2000 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
