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Original article| Volume 40, ISSUE 6, P452-456, September 15, 1996

Electroencephalography in schizophrenic patients: Comparison between neuroleptic-naive state and after treatment

  • Yasuko Nagase
    Correspondence
    Address reprint requests to Dr. Yasuko Nagase, Department of Neuropsychiatry, Tokyo Medical and Dental University, School of Medicine, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113, Japan.
    Affiliations
    Department of Neuropsychiatry, Tokyo Medical and Dental University, School of Medicine, Tokyo, Japan
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  • Yoshiro Okubo
    Affiliations
    Department of Neuropsychiatry, Tokyo Medical and Dental University, School of Medicine, Tokyo, Japan
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  • Michio Toru
    Affiliations
    Department of Neuropsychiatry, Tokyo Medical and Dental University, School of Medicine, Tokyo, Japan
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      This paper is only available as a PDF. To read, Please Download here.
      Electroencephalography of 12 schizophrenic patients was recorded in a neuroleptic-naive state and after 6.2 ± 1.1 months of treatment, when they were on medication and in partial remission. Compared with age- and sex-matched controls, the neuroleptic-naive schizophrenics had less alpha 2 power. In the medicated state, alpha 2 power and slow-wave power were reduced as compared with the neuroleptic-naive state. The reduction in alpha 2 power may occur from the early stage of the disease and progress even though the patients are medicated and clinically improved.

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