Brief report| Volume 40, ISSUE 8, P804-806, October 15, 1996

Effect of the cholecystokinin-B receptor antagonist L-365,260 on lactate-induced panic attacks in panic disorder patients

      This paper is only available as a PDF. To read, Please Download here.

      Key Words

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Biological Psychiatry
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • American Psychiatric Association
        Diagnostic and Statistical Manual of Mental Disorders. 1987; (Washington, DC)
        • Bradwejn J
        • Koszycki D
        • Payena R
        • et al.
        Study of the replication of action of cholecystokinin in panic disorders.
        Am J Psychiatry. 1992; 149: 962-964
        • Bradwejn J
        • Koszycki D
        • Couëtoux du Tertre A
        • et al.
        The panicogenic effects of CCK-tetrapeptide are antagonized by L-365,260, a central CCK receptor antagonist in patients with panic disorder.
        Arch Gen Psychiatry. 1994; 51: 486-493
        • Coplan JD
        • Liebowitz MR
        • Gorman JM
        • et al.
        Noradrenergic function in panic disorder effects of intravenous clonidine pretreatment on lactate induced panic.
        Biol Psychiatry. 1992; 31: 135-146
        • Cowley DS
        • Dager SR
        • Roy-Byrne PP
        • Avery DH
        • Dunner DL
        Lactate vulnerability after alprazolan versus placebo treatment of panic disorder.
        Biol Psychiatry. 1991; 30: 49-56
        • den Boer JA
        • Westenberg HGM
        Behavioural biological and neuroendocrine concomitants of lactate-induced panic anxiety.
        Biol Psychiatry. 1989; 26: 612-622
        • Liebowitz MR
        • Fyer AJ
        • Gorman JM
        • et al.
        Lactate provocation of panic attacks: I. Clinical and behavioral findings.
        Arch Gen Psychiatry. 1984; 41: 764-770
        • Rifkin A
        • Klein DF
        • Dillon D
        Blockade by imipramine or desipramine of panic induced by sodium lactate.
        Am J Psychiatry. 1981; 138: 676-677
        • van Megen HJGM
        • den Boer JA
        • Westenberg HGM
        On the significance of cholecystokinin receptors in panic disorder.
        Prog Neuropsychopharmacol. 1994; 18: 1235-1246
        • Westenberg HGM
        • den Boer JA
        Neuropharmacology of anxiety.
        in: Handbook of Anxiety and Depression. Marcel Dekker, Washington DC1994: 405-447