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Twenty-eight psychiatric patients with computerized tomography (CT) findings of ventricular
abnormality most likely to result from prenatal/perinatal lesions (VA group) were
compared to 28 sex- and age-matched psychiatric patients with normal neuroradiological
findings (NCT group). The neuroradiological rater was blind to clinical psychiatric
diagnoses and, vice versa, clinical diagnoses were established without knowledge of
neuroradiological findings. A polydiagnostic approach (DSM-III-R, ICD-10, Leonhard
Classification) was used for psychiatric diagnostic workup. Significantly more patients
with cycloid psychoses (according to Leonhard's original description) were found in
VA as compared to NCT patients. According to DSM-III-R and ICD-10, VA and NCT groups
did not differ significantly regarding diagnostic distribution. Ventricular abnormalities
that may reflect sequels of birth complications and/or adverse events during pregnancy
may constitute one of the risk factors for developing cycloid psychosis as originally
described by Leonhard.
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Article info
Publication history
Received in revised form:
May 11,
1995
Received:
November 30,
1994
Identification
Copyright
© 1996 Society of Biological Psychiatry. Published by Elsevier Inc.
