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Classical analysis of the spontaneous sleep EEG in depressive disorder commonly reveals
alterations of sleep continuity, number of awakenings, slow-wave sleep, and REM sleep
compared to healthy controls; however, conventional analysis can not help understand
dynamic differences of the sleep EEG during different sleep stages. In order to elicit
qualitative alterations of information processing between depressives and healthy
controls, we measured late components of auditory and visual evoked potentials (AEPs
and VEPs) during different sleep stages of 15 depressive inpatients and in a sex-
and age-matched control group from scalp positions Fz, Cz, and Pz. According to linear system theory, we then computed the amplitude frequency characteristic
(AFC) from averaged AEPs and VEPs in different sleep stages. These AFCs describe the
input/output relation of the system under study leading to a characterization of the
transfer properties of the brain during sleep in depression. Our investigations showed
that information processing appears characteristically altered in depression during
non-REM sleep for both auditory and visual stimulation compared to healthy controls.
The transfer properties for processing auditory as well as visual information during
REM sleep do not appear dynamically impaired in depressive disorder.
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Article info
Publication history
Received in revised form:
August 7,
1995
Received:
February 3,
1995
Footnotes
This work was supported by the Deutsche Forschungsgemeinschaft DFG (Ro 809/4-1). It contains essential parts of the doctoral dissertation of Tatjana Prentice-Cuntz.
Identification
Copyright
© 1996 Society of Biological Psychiatry. Published by Elsevier Inc.
