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Sleep measures were obtained in 16 depressed and 21 control adolescents following
1 week of adherence to a uniformly imposed and strictly enforced sleep/wake schedule.
Three nights of baseline electroencephalographic (EEG) sleep on the same 10:00 pm to 7:00 am schedule revealed prolonged sleep latency and reduced rapid eye movement (REM) latency
in the depressed adolescents. Following baseline measures, sleep was restricted for
2 nights (10:00 pm–4:00 am) and measures of recovery sleep were obtained showing further sleep latency differences.
There was no evidence for delta sleep changes or sleep continuity differences in depressed
adolescents. These results suggest that control over sleep/wake schedules is an important
methodological issue in adolescent sleep studies. Furthermore, the findings are consistent
with a larger body of evidence indicating that dysregulation near sleep onset represents
a primary psychobiological change in early-onset depression.
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Article info
Publication history
Received in revised form:
March 7,
1995
Received:
November 14,
1994
Footnotes
These results were presented in part at the Annual Meeting of the American Sleep Disorders Association in Boston, Massachusetts, June of 1994.
This work was supported by NIMH Grant #R29-MH46510 to Dr. Dahl.
Identification
Copyright
© 1996 Society of Biological Psychiatry. Published by Elsevier Inc.
