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Saccadic and smooth pursuit eye movements were recorded in schizophrenic patients,
nonschizophrenic psychiatric patients, and normal controls. Both schizophrenic subjects
and psychiatric controls demonstrated greater increases in error rates and greater
delays in generating antisaccades than did normal controls. Schizophrenic patients
with impaired smooth pursuit tracking showed greater increases in error rates in the
antisaccade task than did schizophrenic patients with normal pursuit. Among psychiatric
controls, increased errors on the antisaccade task were unrelated to pursuit performance.
The small size of this group, however, reduces the power to detect a relation between
smooth pursuit tracking and performance on the antisaccade task. Although most patients
were receiving one or more medications, some of which can affect eye movements, medication
state in this study did not account for differences we report in dependent variables.
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Article info
Publication history
Received in revised form:
April 15,
1994
Received:
May 30,
1992
Footnotes
This work was supported in part by USPHS Grants MH31340, MH44866, MH31154, and MH K05 01021 awarded to the second author, and by the Stanley Foundation Research Award, awarded to the first author.
Identification
Copyright
© 1995 Society of Biological Psychiatry. Published by Elsevier Inc.
