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Original article| Volume 37, ISSUE 2, P72-84, January 15, 1995

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Microarchitectural findings in sleep EEG in depression: Diagnostic implications

  • Roseanne Armitage
    Correspondence
    Address reprint requests to Dr. Roseanne Armitage, Sleep Study Unit, Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, Texas, 75235-9070.
    Affiliations
    Sleep Study Unit, Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA
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DOI:https://doi.org/10.1016/0006-3223(94)00082-E
Microarchitectural findings in sleep EEG in depression: Diagnostic implications
Previous ArticleSleep microarchitecture in depression: Commentary
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      A 10-year review of sleep electroencephalogram (EEG)-frequency analysis in depression reveals several consistent microarchitectural abnormalities. Decreased delta amplitude or incidence, particularly in the first 100 min of sleep, has been reported. Elevated fast-frequency EEG has been shown in both remitted and symptomatic depressed patients, especially in the right hemisphere. Further, interhemispheric coherence is reduced in both depressed groups. These microarchitectural features may not be present in narcolepsy, obsessive-compulsive disorders, or schizophrenia, despite similarities in sleep-stage characteristics. Collectively, these findings suggest that computer analysis of the sleep EEG may differentiate depressed patients from normal controls and from other clinical populations.

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      Article info

      Publication history

      Received in revised form: March 10, 1994
      Received: November 30, 1993

      Identification

      DOI: https://doi.org/10.1016/0006-3223(94)00082-E

      Copyright

      © 1995 Society of Biological Psychiatry. Published by Elsevier Inc.

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