Prodromal symptoms of depression and self-administration of lithium

  • Takeshi Terao
    Address reprint requests to Takeshi Terao, M.D., Department of Psychiatry, University of Occupational and Environmental Health, Yahatanishi-ku, Kitakyushu 807, Japan.
    From the Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Japan
    Search for articles by this author
  • Author Footnotes
    1 The author would like to thank Professor Kazuhiko Abe for his Valuable comments on the manuscript.
      This paper is only available as a PDF. To read, Please Download here.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Biological Psychiatry
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Abou-Saleh M.T.
        • Coppen A.
        The efficacy of low-dose lithium: Clinical, psychological and biological correlates.
        J Psychiatr Res. 1989; 23: 157-162
        • Blier P.
        • de Montigny C.
        Short-term lithium administration enhances serotonergic neurotransmission: Electrophysiological evidence in the rat CNS.
        Eur J Pharmacol. 1985; 113: 69-77
        • Fava G.A.
        • Kellner R.
        Prodromal symptoms in affective disorders.
        Am J Psychiatry. 1991; 148: 823-830
        • Fava G.A.
        • Grandi S.
        • Canestrari R.
        • Molner G.
        Prodromal symptoms in primary major depressive disorder.
        J Affective Disord. 1990; 19: 149-152
        • Hopkinson G.
        The onset of affective illness.
        Psychiatr Neurol (Basel). 1963; 146: 133-140
        • Hopkinson G.
        The prodromal phase of the depressive psychosis.
        Psychiatr Neurol (Basel). 1965; 149: 1-6
        • Kupfer D.J.
        • Frank E.
        • Perel J.M.
        The advantage of early treatment intervention in recurrent depression.
        Arch Gen Psychiatry. 1989; 46: 771-775
        • Terao T.
        • Yanagihara N.
        • Abe K.
        • Izumi F.
        Lithium chloride stimulates catecholamine synthesis and secretion in cultured bovine adrenal medullary cells.
        Biol Psychiatry. 1992; 31: 1038-1049
        • Watanabe S.
        • Ishino H.
        • Otsuki S.
        Double-blind comparison of lithium carbonate and imipramine in treatment of depression.
        Arch Gen Psychiatry. 1975; 32: 659-668