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Original article| Volume 33, ISSUE 5, P326-334, March 01, 1993

Ambulatory polysomnography of never-depressed borderline subjects: A high-risk approach to rapid eye movement latency

  • Marco Battaglia
    Correspondence
    Address reprint requests to Dr. Marco Battaglia, Department of Neuropsychiatric Sciences, Istituto di Ricovero a Carattere Scientifico, 29 Via Prinetti, 20127 Milan, Italy
    Footnotes
    Affiliations
    Department of Neuropsychiatric Sciences, University of Milan School of Medicine, S. Raffaele Hospital, Istituto di Ricovero a Carattere Scientifico, Milan, Italy
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  • Luigi Ferini-Strambi
    Footnotes
    Affiliations
    Department of Neurology, University of Milan School of Medicine, S. Raffaele Hospital, Istituto di Ricovero a Carattere Scientifico, Milan, Italy
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  • Salvatore Smirne
    Footnotes
    Affiliations
    Department of Neuropsychiatric Sciences, University of Milan School of Medicine, S. Raffaele Hospital, Istituto di Ricovero a Carattere Scientifico, Milan, Italy
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  • Luana Bernardeschi
    Footnotes
    Affiliations
    Department of Neurology, University of Milan School of Medicine, S. Raffaele Hospital, Istituto di Ricovero a Carattere Scientifico, Milan, Italy
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  • Laura Bellodi
    Footnotes
    Affiliations
    Department of Neuropsychiatric Sciences, University of Milan School of Medicine, S. Raffaele Hospital, Istituto di Ricovero a Carattere Scientifico, Milan, Italy
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  • Author Footnotes
    ∗ We wish to thank our patients for their collaboration in this study, also Roberto Cavallaro, M.D., Grazia Regazzetti, M.D., Viviana Brancato, M.D., and Betty Rubin, Ph.D., for their help.
DOI:https://doi.org/10.1016/0006-3223(93)90321-4
Ambulatory polysomnography of never-depressed borderline subjects: A high-risk approach to rapid eye movement latency
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      Abstract

      The sleep parameters of never-depressed borderline subjects and age- and sex-matched normal controls were compared by continuous 48-hr ambulatory electroencephalographic (EEG) monitoring. Borderline subjects had a significantly shorter rapid eye movement latency, normal architecture of rapid eye movements sleep, and had familial risks for mood disorders four times greater than in the families of controls. Reduced latency of rapid eye movement can be a trait indicator of liability to depression, present before the clinical appearance of the disorder, and demonstrable in a putative high-risk population.

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      Article info

      Publication history

      Received in revised form: September 10, 1992
      Received: April 22, 1992

      Identification

      DOI: https://doi.org/10.1016/0006-3223(93)90321-4

      Copyright

      © 1993 Published by Elsevier Inc.

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