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A familial/genetic study of plasma serine and glycine concentrations

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      Abstract

      Plasma serine and glycine contractions were assayed in a sample of 28 nuclear families (n = 108). Complex segregation analysis of these familial data reveals significant genetic control of concentrations via a single major gene locus. The serine and glycine metabolizing enyme serine hydroxymethyltransferase (SHMT) is suggested as the most likely candidate for this single major gene locus.

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