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A low plasma prolactin concentration has been reported to be associated with an increased risk of subsequent relapse in patients with schizophrenia. Prolactin concentration was measured in samples from stable schizophrenic men who were outpatients just prior to neuroleptic withdrawal. No relationship between prolactin concentration and time to subsequent relapse was found. Prolactin concentration may predict time to relapse only in populations characterized by specific demographic features or medication history.
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Received in revised form: July 20, 1992
Received: March 1, 1991
☆Supported in part by NIMH grants MH-40279 and MH-35996.
© 1992 Published by Elsevier Inc.