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Abstract
There are no reports of an association between obsessive-compulsive disorder and cingulate epilepsy in childhood. We report the behavioral, cognitive, and EEG findings in a young girl with medically resistant seizures and severe obsessive-compulsive symptomatology. Her Scalp EEG and neuropsychological test scores suggested right frontal lobe dysfunction. The intractability of her seizures and progressive intellectual and psychosocial deterioration prompted evaluation for excisional surgery. Intracranial EEG recording demonstrated a focal seizure origin in the right anterior cingulate gyrus. Cingulotomy resulted in freedom from seizures and significant improvement in her obsessive-compulsive symptoms.
References
- Cingulotomy for psychiatric illness: Report of 13 years' experience.in: Sweet W.H. Obrador S. Martin-Rodriguez J.S. Neurosurgical Treatment in Psychiatry, Pain, and Epilepsy. University Park Press, Baltimore1977: 333-353
- Local cerebral glucose metabolic rates in obsessive-compulsive disorder—A comparison with rates in unipolar depression and in normal controls.Arch Gen Psychiatry. 1987; 44: 211-218
- Computerized tomography and neuropsychological test measures in adolescents with obsessive-compulsive disorder.Am J Psychiatry. 1984; 141: 363-369
- Local cerebral glucose metabolic rates in obsessive-compulsive disorder.Arch Gen Psychiatry. 1990; 47: 840-848
- Neuropsychological and power spectral EEG investigations of the obsessive-compulsive syndrome.Biol Psychiatry. 1978; 14: 119-130
- Striatal IMP-spect decrease in obsessive-compulsive disorder, normalized by pharmacotherapy.Neuropsychiatry Neuropsychol Behav Neurol. 1989; 2: 290-300
- Signs of central nervous system dysfunction in obsessive-compulsive disorder.Arch Gen Psychiatry. 1990; 47: 27-32
- Neurological and neuropsychological studies of patients with obsessive-compulsive disorder.Biol Psychiatry. 1983; 18: 741-751
- Criteria for identifying cingulate epilepsies.Epilepsia. 1970; 11: 41-47
- Connections of the frontal lobe with the limbic system.in: Laitinen L.V. Livingston K.E. Surgical Approaches in Psychiatry. Proceedings of the Third International Congress of Psychosurgery. Medical and Technical Publishing, Cambridge, England: Lancaster1973: 303-314
- A case of self-inflicted leucotomy.Br J Psychiatry. 1987; 151: 855-857
- Cerebral glucose metabolism in childhood-onset obsessive-compulsive disorder.Arch Gen Psychiatry. 1989; 46: 518-523
- Endogenous event-related potentials in obsessive-compulsive disorder.Biol Psychiatry. 1990; 28: 92-98
- Imperative ideas.Brain. 1894; 17: 179-195
Article info
Publication history
Received in revised form:
June 10,
1991
Received:
March 8,
1991
Identification
Copyright
© 1991 Published by Elsevier Inc.