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Research Article| Volume 28, ISSUE 4, P292-296, August 15, 1990

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Effect of yohimbine on plasma homovanillic acid in panic disorder patients and normal controls

  • George N.M. Gurguis
    Affiliations
    From the Section on Anxiety and Affective Disorders, Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland, USA
    Search for articles by this author
  • Thomas W. Uhde
    Correspondence
    Address reprint requests to Dr. Thomas W. Uhde, Chief, Section on Anxiety and Affective Disorders, Biological Psychiatry Branch, National Institute of Mental Health, 9000 Rockville Pike, Building 10, Room 3S-239, Bethesda, MD 20892, USA.
    Affiliations
    From the Section on Anxiety and Affective Disorders, Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland, USA
    Search for articles by this author
DOI:https://doi.org/10.1016/0006-3223(90)90656-M
Effect of yohimbine on plasma homovanillic acid in panic disorder patients and normal controls
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      Abstract

      The effects of oral yohimbine (20 mg) or placebo or both drugs on plasma homovanillic acid (HVA) were evaluated in patients with panic disorder and normal controls. Panic disorder patients had similar HVA values at baseline compared with normal controls, and yohimoine failed to produce appreciable changes in HVA in both groups. These findings are discussed within the context of catecholaminergic theories of panic disorder.
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      Article info

      Publication history

      Received in revised form: January 23, 1990
      Received: July 4, 1989

      Identification

      DOI: https://doi.org/10.1016/0006-3223(90)90656-M

      Copyright

      © 1990 Published by Elsevier Inc.

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