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Research Article| Volume 28, ISSUE 8, P697-704, October 15, 1990

A cross-sectional study of the effects of depression on REM latency

  • Donna E. Giles
    Correspondence
    Address reprint requests to Dr. D. E. Giles, Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O'Hara Street, Pittsburgh, PA 15213.
    Footnotes
    Affiliations
    From the Western Psychiatric Institute and Clinic Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
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  • Howard P. Roffwarg
    Footnotes
    Affiliations
    Mental Health Clinical Research Center, Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75235, USA
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  • A.John Rush
    Footnotes
    Affiliations
    Mental Health Clinical Research Center, Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75235, USA
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  • Author Footnotes
    1 We would like to thank the sleep technicians for technical support, Barbara A. Etzel and Jodi Terry for help with data analyses, and Vicki Gonze and JoAnn Matthews for preparation of this manuscript. T
DOI:https://doi.org/10.1016/0006-3223(90)90456-C
A cross-sectional study of the effects of depression on REM latency
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      Abstract

      In a cross-sectional design to address the effects of the course of depression on rapid-eye-movement (REM) latency, we have matched patients in their first-episode with (1) age-matched patients with recurrent depression, (2) onset-matched patients with recurrent depression, and (3) age-matched normal control subjects. Patients were also matched for sex and treatment site (inpatient or outpatient). No differences were found in REM latency for the three depressed groups, and all had lower REM latency than normals. This finding is taken as support for stable REM latency throughout the course of depression.
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      Article info

      Publication history

      Received in revised form: March 23, 1990
      Received: January 26, 1990

      Footnotes

      ☆The study was supported in part by NIMH grants MH-35370, MH-39531, and a grant from the Upjohn Pharmaceutical Company.

      Identification

      DOI: https://doi.org/10.1016/0006-3223(90)90456-C

      Copyright

      © 1990 Published by Elsevier Inc.

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