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Article| Volume 27, ISSUE 10, P1103-1115, May 15, 1990

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Event-related potential correlates of impaired attention in schizophrenic children

  • Robert J. Strandburg
    Affiliations
    From the Department of Pscyhiatry and Biobehavioral Sciences, University of California, Los Angeles, USA

    Department of Psychology, Rhodes College, Memphis, TN, USA
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  • James T. Marsh
    Correspondence
    Address reprint requests to James T. Marsh, Ph.D., Department of Psychiatry & Biobehavioral Sciences, NPI 68–251, UCLA School of Medicine, 760 Westwood Plaza, Los Angeles, CA 90024 USA
    Affiliations
    From the Department of Pscyhiatry and Biobehavioral Sciences, University of California, Los Angeles, USA

    Brain Research Institute, University of California, Los Angeles, USA
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  • Warren S. Brown
    Affiliations
    From the Department of Pscyhiatry and Biobehavioral Sciences, University of California, Los Angeles, USA

    Brain Research Institute, University of California, Los Angeles, USA

    Fuller Seminary, Graduate School of Psychology, Pasadena, CA USA
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  • Robert F. Asarnow
    Affiliations
    From the Department of Pscyhiatry and Biobehavioral Sciences, University of California, Los Angeles, USA
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  • Donald Guthrie
    Affiliations
    From the Department of Pscyhiatry and Biobehavioral Sciences, University of California, Los Angeles, USA

    Division of Biostaticsics, School of Public Health, University of California, Los Angeles, CA, USA
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  • Jerilyn Higa
    Affiliations
    From the Department of Pscyhiatry and Biobehavioral Sciences, University of California, Los Angeles, USA
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DOI:https://doi.org/10.1016/0006-3223(90)90047-6
Event-related potential correlates of impaired attention in schizophrenic children
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      Abstract

      Electrophysiological correlates of focused attention were studied in 13 schizophrenic and 19 age- and gender-matched children. Subjects performed a version of the Continuous Performance Task (CPT) in which a target was designated as any digit from 0 through 9 occurring on two successive stimulus presentations. Signal digits were surrounded by distractor digits which varied in position, value, and number. Event-related potentials (ERPs) elicited by each stimulus of a target pair were recorded from midline and homologous parietal, temporal, and occipital electrode placements. Schizophrenic children made significantly more errors of omission and commission than normal children. The amplitude and time course of the intertrial CNV was the same for both groups. There was a circumscribed amplitude asymmetry, left smaller than right, for the P1/N1 and P2 measures which was greater in normal than in schizophrenic children. The P3 component was significantly larger to the second stimulus of the target pair than to the first for both groups and larger for the normal than the schizophrenic children to both stimuli.
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      Article info

      Publication history

      Received in revised form: May 20, 1989
      Received: February 1, 1989

      Footnotes

      ☆Supported by NIMH Research Grant MH37665.

      Identification

      DOI: https://doi.org/10.1016/0006-3223(90)90047-6

      Copyright

      © 1990 Published by Elsevier Inc.

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