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Abstract
The circadian rhythm of several plasma hormones (prolactin, growth hormone, adrenocorticotropic
hormone (ACTH), cortisol, and melatonin) was simultaneously evaluated in 23 women
with anorexia nervosa (AN), in 27 obese (OB) women, and in gender and age-matched
healthy controls. A trend toward similar alterations of the circadian pattern of the
different hormones was observed in the two groups of patients, with the exception
of plasma growth hormone (GH), which exhibited nutrition-dependent impairments. The
timing of the peaks for each hormonal rhythm revealed the existence of an internal
desynchronization in both eating disorders.
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References
- The pineal gland: A neurochemical transducer.Science. 1974; 184: 1341-1344
- Hormonal responses to short-term fasting in postmenopausal women.J Clin Endocrinol Metab. 1985; 60: 1120-1126
- Inferential statistical methods for estimating and comparing cosinor parameters.Chronobiologia. 1982; IX: 397-439
- Cortisol secretion and metabolism in anorexia nervosa.N Engl J Med. 1977; 296: 190-193
- Rhythmic and dynamic aspects of multiple neuroendocrine secretions related to sexual function in anorexia nervosa.in: Pancheri P. Zichella L. Biorhythms and Stress in the Physiopathology of Reproduction. Hemisphere Publishing Corporation, New York1988: 519-534
- Anorexia nervosa and obesity: A common psychoendocrine approach.in: Ferrari E. Brambilla F. Disorders of Eating Behaviour: A Psychoneuroendocrine Approach. Pergamon Press, Oxford-New York1986: 259-271
- Manifestations of hypothalamic obesity in man: A comprehensive investigation of 8 patients and a review of the literature.Medicine. 1975; 54: 301-330
- Endocrine profiles in anorexia nervosa.in: Vigersky R.A. Anorexia Nervosa. Raven Press, New York1977: 123-135
- Differences in nocturnal melatonin secretion between melancholic depressed patients and control subjects.Am J Psychiatry. 1985; 142: 811-815
- Plasma melatonin increases during exercise in women.J Clin Endocrinol Metab. 1981; 53: 224-225
- Alterations in serum cortisol and its binding characteristics in anorexia nervosa.J Clin Endocrinol Metab. 1979; 49: 406-411
- Effect of food restriction on serum melatonin in male rats.Neuroendocrinol (Letters). 1985; 7: 147
- Simultaneous study of cortisol, growth hormone, and prolactin nyctohemeral variations in normal and obese subjects. Influence of prolonged fasting in obesity.Clin Endocrinol. 1978; 9: 15-26
- Nocturnal hormonal profiles and sleep patterns in relation to weight loss and dietary changes following ileo-jejunal bypass in a massively obese population.in: Ferrari E. Brambilla F. Disorders of Eating Behaviour: A Psychoneuroendocrine Approach. Pergamon Press, Oxford-New York1986: 141-148
- Hormonal changes after jet lag in normal man.in: Mendlewicz J. Van Prag H.M. Biological Rhythms and Behaviour. Karger, Basel1983: 60-63
- Relation between weight gain and hypothalamic pituitary-adrenal function in patients with anorexia nervosa.J Steroid Biochem. 1980; 13: 529-537
- Diagnostic criteria for use in psychiatric research.Arch Gen Psychiatry. 1972; 26: 57-63
- Anorexia nervosa: An overview of hypothalamic-pituitary function.in: Brown G.M. Koslow S.H. Reichlin S. Neuroendocrinology and Psychiatric Disorder. Raven Press, New York1984: 301-314
- Psychoneuroendocrine profiles of disorders of eating behaviour.in: Ferrari E. Brambilla F. Disorders of Eating Behaviour: A Psychoneuroendocrine Approach. Pergamon Press, Oxford-New York1986: 1-8
- Abnormal hypothalamic-pituitary-adrenal function in anorexia nervosa.N Engl J Med. 1986; 314: 1335-1342
- Chronobiology.Ann Rev Physiol. 1969; 31: 675-725
- A rating scale for depression.J Neurol Neurosurg Psychiatry. 1960; 23: 56-62
- Diet and prolactin release.Lancet. 1976; ii: 806-807
- Nocturnal hormonal profiles in massive obesity, anorexia nervosa and normal females.J Psychosom Res. 1976; 20: 595-604
- Central nervous system amine metabolism in anorexia nervosa.in: 133rd Ann Meet Am Psychiatr Assoc Syllabus and Scientific Proceedings. 1980: 326
- Altered norepinephrine following long-term weight recovery in patients with anorexia nervosa.Psychiatry Res. 1985; 14: 333-342
- Relation of body fat distribution to metabolic complications of obesity.J Clin Endocrinol Metab. 1982; 54: 254-260
- Impaired hypothalamic control of prolactin secretion in massive obesity.Lancet. 1979; i: 747-749
- Krieger D.T. Endocrine Rhythms. Raven Press, New York1979
- Diurnal rhythm of melatonin action on sexual maturation of male rats.Neuroendocrinology. 1974; 38: 261-268
- Noradrenergic function in the medial hypothalamus: Potential relation to anorexia nervosa and bulimia.in: Pirke K.M. Ploog D. The Psychobiology of Anorexia Nervosa. Springer Verlag, Berlin1984: 35-45
- Effect of nalozone on the nocturnal rise of rat pineal melatonin content.Eur J Pharmacol. 1984; 98: 261-264
- Hypothalamic dysfunction in patients with anorexia nervosa.Medicine. 1974; 53: 147-159
- Diurnal hypersecretion of growth hormone in depression.J Clin Endocrinol Metab. 1985; 60: 505-512
- Human growth hormone in protein calorie malnutrition.in: Pecile A. Muller E.E. Growth and Growth Hormone. Excerpta Medica, Amsterdam1973: 389-401
- 24 hour sleep-wake cycle of LH and cortisol during starvation in healthy subjects and in anorexia nervosa.Acta Endocrinol. 1982; 99: 83-84
- The pineal gland: Basic implications and clinical correlations.Endocrinol Rev. 1984; 5: 282-308
- Chronobiology of growth hormone secretion.Chronobiologia. 1977; IV: 217-246
- The pineal and its hormones in the control of reproduction in mammals.Endocrine Rev. 1980; 1: 109-131
- Daily administration of melatonin delays rat vaginal opening and disrupts the first estrous cycles: Evidence that these effects are synchronized by the onset of light.Endocrinology. 1985; 116: 779-780
- Effect of melatonin on the reproductive systems of male and female Syrian hamsters: A diurnal rhythm in sensitivity to melatonin.Endocrinology. 1976; 99: 1534-1541
- The degree of masculine differentiation of obesities: A factor determining predisposition to diabetes, atherosclerosis, gout and uric calculus disease.Am J Clin Nutr. 1956; 4: 20-25
- The production rate of cortisol declines during recovery from anorexia nervosa.J Clin Endocrinol Metab. 1981; 53: 203-205
- The circadian pattern of melatonin and its positive relationship with progesterone in women.J Clin Endocrinol Metab. 1986; 63: 323-328
- Circadian rhythms mechanisms in affective illness and in antidepressant drug action.Pharmakopsychiatry. 1982; 15: 31-39
- Circadian rhythms in melatonin and cortisol secretion in depression.in: Usdin E. Frontiers in Biochemical and Pharmacological Research in Depression. Raven Press, New York1984: 197-207
- Impaired growth hormone response to growth-hormone-releasing factor in obesity.N Engl J Med. 1984; 311: 1403-1407
- The uptake of (H) melatonin in endocrine and nervous tissues and the effects of constant light exposure.J Pharmacol Exp Ther. 1964; 143: 314-318
Article info
Publication history
Received in revised form:
June 19,
1989
Received:
March 24,
1989
Identification
Copyright
© 1990 Published by Elsevier Inc.