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Abstract
Cranial computed tomography (CT) was performed in 12 patients with anorexia nervosa,
revealing that the majority of the patients displayed ventricular dilatation and/or
sulcal widening. In addition, regional cerebral blood flow (rCBF) was measured at
admission and once again after weight gain, using xenon-133 dynamic single-photon
emission tomography (dSPECT). The mean flow rates assessed at the first examination
did not significantly differ from those assessed at the second examination and from
those of a control group. There was a significant inverse relationship between the
size of the cerebrospinal fluid spaces and the cerebral blood flow in the anorectics;
a decrease in ventricular size after weight gain was associated with an increase in
cerebral blood flow in this area. This finding, however, has to be interpreted with
caution, as partial volume effects render the flow rates ambiguous in brain areas,
which, in addition to neuronal tissue, also include ventricular and sulcal structures.
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Article info
Publication history
Received in revised form:
June 20,
1988
Received:
March 11,
1988
Identification
Copyright
© 1989 Published by Elsevier Inc.
