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Cranial computed tomography (CT) was performed in 12 patients with anorexia nervosa, revealing that the majority of the patients displayed ventricular dilatation and/or sulcal widening. In addition, regional cerebral blood flow (rCBF) was measured at admission and once again after weight gain, using xenon-133 dynamic single-photon emission tomography (dSPECT). The mean flow rates assessed at the first examination did not significantly differ from those assessed at the second examination and from those of a control group. There was a significant inverse relationship between the size of the cerebrospinal fluid spaces and the cerebral blood flow in the anorectics; a decrease in ventricular size after weight gain was associated with an increase in cerebral blood flow in this area. This finding, however, has to be interpreted with caution, as partial volume effects render the flow rates ambiguous in brain areas, which, in addition to neuronal tissue, also include ventricular and sulcal structures.
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- Diagnostic and Statistical Manual of Mental Disorders. American Psychiatric Association, Washington, DC1987 (revised) ed. 3.
- Reversible and non-reversible enlargement of cerebrospinal fluid spaces in anorexia nervosa.Neuroradiology. 1985; 27: 304-312
- Single-photon tomography study of regional cerebral blood flow after stroke: Concise communication.J Nucl Med. 1981; 22: 1049-1053
- 133-Xe-DSPECT (dynamische single photon emissions CT).Fortschr Röntgenstr. 1983; 139: 351-358
- Dynamic SPECT with Xe-133: Regional cerebral blood flow in patients with unilateral cerebrovascular disease: Concise communication.J Nucl Med. 1984; 25: 441-446
- A method for calculating regional cerebral blood flow from emission computed tomography of inert gas concentrations.J Comput Assist Tomogr. 1981; 5: 641-645
- Ventricular dilatation on CAT scans of patients with anorexia nervosa.Am J Psychiatr. 1986; 143: 96-98
- Cranial computed tomography findings in anorexia nervosa.J Comput Assist Tomogr. 1977; 1: 410-414
- Diagnostic criteria for use in psychiatric research.Arch Gen Psychiatry. 1972; 26: 57-63
- Neuropsychological correlates of anorexia nervosa.Int J Psychiatry Med. 1981; 11: 285-290
- Die Erkrankungendes vegetativen Systems.in: Handbuch der Inneren Medizin. Springer, Berlin1953: 885-888 (Fünfter Band)
- Prediction of outcome in anorexia nervosa from neuropsychological status.Psychiatry Res. 1981; 4: 79-88
- Encephalographische Befunde bei Anorexia nervosa.Arch Psychiatr Nervenkr. 1961; 202: 183-201
- Regional cerebral glucose metabolism in anorexia nervosa measured by positron emission tomography.Biol Psychiatry. 1987; 22: 43-51
- Two methods for calculating regional cerebral blood flow from emission computed tomography of inert gas concentrations.J Comput Assist Tomogr. 1979; 3: 71-76
- Computed tomography of anorexia nervosa.AJNR. 1983; 4: 437-438
- Cranial computed tomography findings in bulimia.Acta Psychiatr Scand. 1987; 75: 144-149
- Endocrine, metabolic and cranial computed tomographic findings in anorexia nervosa.Biol Psychiatry. 1988; 23: 377-387
- Structural brain abnormalities in patients with bulimia nervosa.Psychiatry Res. 1989; (in press).
- Cranial CT scans in eating disorder patients and controls.Compr Psychiatry. 1985; 26: 136-147
- Regional cerebral blood flow in stroke by 133-xenon inhalation and emission tomography.Stroke. 1981; 12: 284-288
- Pathologie des aspects neurologiques et psychiatriques de quelques manifestations carentielles avec troubles digestifs et neuro-endocriniens.Acta Neurol Belg. 1958; 58: 816-830
- Asymmetric cognitive function in anorexia nervosa.Int J Neurosci. 1984; 24: 37-44
- Neuropsychological test performance of bulimic patients.Int J Neurosci. 1986; 30: 73-80
- Statistical Bulletin of the Metropolitan Life Insurance Co. 1959; 40: 1-17
- Psychobiology of anorexia nervosa.Psychol Med. 1987; 17: 843-859
- Enlargement of cerebrospinal fluid spaces in long-term benzodiazepine abusers.Psychol Med. 1987; 17: 869-873
- Regional cerebral blood flow assessed by 133-Xe inhalation and emission tomography: Normal values.J Comput Assist Tomogr. 1985; 9: 861-866
- A single photon dynamic computer assisted tomograph (DCAT) for imaging brain function in multiple cross sections.J Comput Assist Tomogr. 1980; 4: 230-240
- Learning deficits in adolescents with anorexia nervosa.J Nerv Ment Dis. 1985; 173: 182-184
Received in revised form: June 20, 1988
Received: March 11, 1988
© 1989 Published by Elsevier Inc.