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Abstract
The distinctive theta rhythm that appears at the frontal midline during the performance
of mental tasks has been designated as frontal midline theta (Fmθ). Fmθ shows individual
differences and seems to be related to certain personality traits. In several studies,
it has been indicated that low platelet monoamine oxidase (MAO) activity is also associated
with certain personality traits. In the present study, we found a negative correlation
between the appearance of Fmθ and platelet MAO activity. Subjects with marked extroversion
show a high amount of Fmθ and low MAO activity. It is therefore suggested that Fmθ,
an electrophysiological marker, may be useful in the investigation of monoamine functions
in the central nervous system (CNS) by way of platelet MAO activity, a biochemical
marker.
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References
- Platelet MAO activity: Relationships to clinical and psychometric variables.Schizophr Bull. 1980; 6: 226-231
- The biochemical high-risk paradigm: Behavioral and familial correlates of low platelet monoamine oxidase activity.Science. 1976; 194: 339-341
- Suicide attempts, platelet monoamine oxidase and the average evoked response.Acta Psychiatr Scand. 1977; 56: 69-79
- Platelet monoamine oxidase activity in sensation seekers.Psychiatry Res. 1980; 3: 273-279
- Human platelet monoamine oxidase—A useful enzyme in the study of psychiatric disorders?.Neuroscience. 1982; 7: 1577-1594
- Platelet MAO activity and personality characteristics. A study in schizophrenic patients and normal individuals.Acta Psychiatr Scand. 1981; 63: 479-485
- Amino aicds in plasma and CSF and monoamine metabolites in CSF: Interrelationship in healthy subjects.J Neurochem. 1984; 42: 833-837
- Psychiatric vulnerability, monoamine oxidase, and the average evoked potential.Arch Gen Psychiatry. 1980; 37: 340-345
- Multivariate analytic study of EEG and mental activity in juvenile delinquents.Electroencephalogr Clin Neurophysiol. 1972; 33: 71-80
- Comparison of platelet count and platelet protein methods for determination of platelet MAO activity.Clin Chim Acta. 1979; 96: 15-23
- A correlation between platelet monamine oxidase activity and plasma prolactin concentrations in man.Science. 1979; 206: 479-481
- Catecholamines and monoamine oxidase activity in anxiety.Acta Psychiatr Scand. 1981; 63: 245-252
- Periodic appearance of theta rhythm in the frontal midline area during performance of a mental task.Electroencephalogr Clin Neurophysiol. 1980; 49: 345-351
- Effects of centrally acting drugs on the frontal midline theta activity in man.Electroencephalogr Clin Neurophysiol. 1981; 52: 70
- Effects of centrally acting drugs on the frontal midline theta activity.Electroencephalogr Clin Neurophysiol. 1982; 54: 28
- The relationship between appearance of Fmθ and plasma catecholamines.Clin Electroencephalogr (Osaka). 1985; 27 (in Japanese).: 495-500
- The influence of alcohol on the appearance of frontal midline theta activity.Folia Psychiatr Neurol Jpn. 1980; 34: 1-8
- Biological and behavioral consequences of alterations in monoamine oxidase activity.Schziophr Bull. 1980; 6: 355-367
- Reduced monoamine oxidase activity in blood platelets from bipolar depressed patients.Am J Psychiatry. 1972; 128: 1351-1357
- Reduced monoamine oxidase activity in blood platelets from schizophrenic patients.Nature. 1972; 238: 225-226
- Biogenic amine-related enzymes and personality variations in normals.Psychol Med. 1977; 7: 149-157
- Effects of DM-1417 (TRH-analog) on the appearance of Fmθ.Folia Psychiatr N enrol Jpn. 1985; 39: 105
- The standard of E score derived from the group of 851 university students.in: The New Personality Inventory—Maudsley Personality Inventory. Seishin-Shobo, Tokyo1969: 141 (in Japanese)
- Why do alcoholics have low platelet monoamine oxidase activity?.in: Biological and/or Genetic Factors in Alcoholism. Res Monograph No. 9. US Government Printing Office, Washington, DC1983: 109-130
- Some rationale behind the use of monoamine oxidase activity as a biological marker.Trends Pharmacol Sci. 1983; 4: 339-341
- Platelet MAO activity and monoamine metabolites in cerebrospinal fluid in depressed and suicidal patients and in healthy controls.Psychiatry Res. 1981; 4: 21-29
- Monoamine oxidase activity in platelets as related to monoamine oxidase activity and monoaminergic function in the brain.in: Recent Advances in Neuropsychopharmacologv. Advances in the Biosciences. vol 13. Pergamon Press, Oxford1981: 195-201
- Enzymes related to biogenic amine metabolism and personality characteristics in depressed patients.Acta Psychiatr Scand. 1980; 61: 477-484
- Life events and biological vulnerability: A study of life events and platelet MAO activity in depressed patients.Psychiatry Res. 1984; 12: 111-120
- Studies on biogenic amine metabolizing enzymes (DBH, COMT, MAO) and pathogenesis of affective illness. III. Platelet monoamine oxidase activity in endogenous depression.Acta Psychiatr Scand. 1983; 67: 101-108
- Genetics of platelet MAO activity in discordant schizophrenic and normal twins.Br J Psychiatry. 1983; 142: 560-565
- Impulsive cognitive style and inability to tolerate boredom: Psychobiological studies of temperamental vulnerability.in: Zuckerman M Biological Bases of Sensation Seeking, Impulsivity and Anxiety. Lawrence Erlbaum Associates, Hillsdale, NJ1983: 123-145
- Impulsivity, nonconformity, and sensation seeking as related to biological markers for vulnerability.Clin Neuropharmacol. 1984; 7: 403
- Psychological correlates of monoamine oxidase activity in normals.J Nerv Ment Dis. 1978; 166: 177-186
- Platelet monoamine oxidase activity in relatives of alcoholics.Arch Gen Psychiatry. 1982; 39: 137-140
- Biological markers for schizophrenia and the biological high-risk approach.J Nerv Ment Dis. 1985; 173: 4-6
- Personality traits to monoarnine oxidase (MAO) activity in platelets.Psychiatry Res. 1984; 12: 11-26
- Sensation seeking and its biological correlates.Psychol Bull. 1980; 88: 187-214
Article info
Publication history
Received in revised form:
March 5,
1987
Received:
November 3,
1986
Identification
Copyright
© 1988 Published by Elsevier Inc.