Research Article| Volume 23, ISSUE 1, P31-43, January 01, 1988

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Frontal midline theta activity and platelet MAO in human subjects

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      The distinctive theta rhythm that appears at the frontal midline during the performance of mental tasks has been designated as frontal midline theta (Fmθ). Fmθ shows individual differences and seems to be related to certain personality traits. In several studies, it has been indicated that low platelet monoamine oxidase (MAO) activity is also associated with certain personality traits. In the present study, we found a negative correlation between the appearance of Fmθ and platelet MAO activity. Subjects with marked extroversion show a high amount of Fmθ and low MAO activity. It is therefore suggested that Fmθ, an electrophysiological marker, may be useful in the investigation of monoamine functions in the central nervous system (CNS) by way of platelet MAO activity, a biochemical marker.
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