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Abstract
Platelet aggregation induced by 5-hydroxytryptamine (5-HT) was used as a measure of
the functional responsiveness of peripheral 5-HT receptors in controls and drug-free
patients suffering from senile dementia of Alzheimer type (SDAT). No significantly
different aggregatory response (5-HTIADP ratio) was noted between the two groups of
subjects. If the receptor mediating this response is a 5-HT2 receptor, there is no evidence to suggest that the functional activity of this system
is abnormal in SDAT.
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Article info
Publication history
Received in revised form:
April 4,
1988
Received:
May 8,
1987
Identification
Copyright
© 1988 Published by Elsevier Inc.
