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Research Article| Volume 22, ISSUE 7, P820-828, July 1987

Sleep EEG in bulimia

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      Abstract

      To evaluate the sleep electroencephalogram (EEG) characteristics of bulimia, all-night sleep EEGs were performed on 11 women meeting DSM-III criteria for bulimia. Comparison groups consisted of young women outpatients with major depression (n = 44) and young normal women (n = 20). The sleep EEGs of the bulimic patients were largely indistinguishable from those of the normal controls, except for a trend toward increased rapid eye movement (REM) density in the first REM period among the bulimic subjects. No differences in any sleep EEG measure were observed between bulimic patients with major depression and those without affective disorder. By contrast, the outpatients with major depression displayed marked sleep continuity disturbances, as well as significantly increased REM intensity and REM density, as compared to normal controls. Implications of these results with respect to the hypothesis that bulimia is related to major affective disorder are discussed.
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      References

        • Akiskal HS
        • Lemmi H
        • Yerevanian B
        • King D
        • Belluomini
        The utility of the REM latency test in psychiatric diagnosis: A study of 81 depressed outpatients.
        Psychiatry Res. 1982; 7: 101-110
        • American Psychiatric Association
        3rd ed. Diagnostic and Statistical Manual of Mental Disorders. American Psychiatric Association, Washington DC1980
        • Cashman MA
        • Coble P
        • McCann BS
        • Taska L
        • Reynolds CF
        • Kupfer DJ
        Sleep markers for major depressive disorder in adolescent patients.
        Sleep Res. 1986; 15: 91
        • Cooper PJ
        • Fairburn CG
        The depressive symptoms of bulimia nervosa.
        Br J Psychiatry. 1986; 148: 268-274
        • Feinberg M
        • Gillin JC
        • Carroll BJ
        • Greden JF
        • Zis AP
        EEG studies of sleep in the diagnosis of depression.
        Biol Psychiatry. 1982; 17: 305-316
        • Frank E
        • Kupfer DJ
        Maintenance treatment of recurrent unipolar depression: Pharmacology and psychotherapy.
        in: Kemali D Racagni G Chronic Treatment in Neuropsychiatry. Raven Press, New York1985: 139-151
        • Gillin JC
        • Duncan W
        • Pettigrew KD
        • Frankel BL
        • Snyder F
        Successful separation of depressed, normal, and insomniac subjects by EEG sleep data.
        Arch Gen Psychiatry. 1979; 36: 85-90
        • Gillin JC
        • Duncan WC
        • Murphy DL
        • Post RM
        • Wehr TA
        • Goodwin FK
        • Wyatt RJ
        • Bunney Jr, WE
        Age-related changes in sleep in depressed and normal subjects.
        Psychiatry Res. 1981; 4: 73-78
        • Gwirtsman HE
        • Roy-Byrne P
        • Yager J
        • Gerner RH
        Neuroendocrine abnormalities in bulimia.
        Am J Psychiatry. 1983; 140: 559-563
        • Hamilton M
        Development of rating scale for primary depressive illness.
        Br J Soc Clin Psychol. 1967; 6: 278-296
        • Hawkins DR
        • Taub JM
        • Van de Castle RL
        Extended sleep (hypersomnia) in young depressed patients.
        Am J Psychiatry. 1985; 142: 905-910
        • Herzog DB
        Are anorectics and bulimics depressed?.
        Am J Psychiatry. 1984; 141: 1594-1597
        • Hudson JI
        • Hudson MS
        Endocrine dysfunction in anorexia nervosa and bulimia: Comparison with abnormalities in other psychiatric disorders and disturbances due to metabolic factors.
        Psychol Dev. 1984; 4: 237-272
        • Hudson JI
        • Pope Jr, HG
        Depression and eating disorders.
        in: Cameron OG Presentations of Depression. John Wiley & Sons, New York1987 (in press).
        • Hudson JI
        • Pope Jr, HG
        • Jonas JM
        • Yurgelun-Todd D
        Family history study of anorexia nervosa and bulimia.
        Br J Psychiatry. 1983; 142: 133-138
        • Hudson JI
        • Pope Jr, HG
        • Jonas JM
        • Yurgelun-Todd D
        Hypothalamic-pituitary-adrenal axis hyperactivity in bulimia.
        Psychiatry Res. 1983; 8: 111-118
        • Hudson JI
        • Pope Jr, HG
        • Jonas JM
        • Yurgelun-Todd
        Phenomenologic relationship between eating disorders and major affective disorder.
        Psychiatry Res. 1983; 9: 345-354
        • Hudson JI
        • Pope Jr, HG
        • Yurgelun-Todd D
        • Jonas JM
        • Frankenburg FR
        Lifetime prevalence of affective and other psychiatric disorders in bulimic outpatients: A controlled study.
        Am J Psychiatry. 1987; (in press).
        • Hughes PL
        • Wells LA
        • Cunningham CJ
        The Dexamethasone Suppression Test in bulimia before and after successful treatment with desipramine.
        J Clin Psychiatry. 1986; 47: 515-517
        • Hughes PL
        • Wells LA
        • Cunningham CJ
        • Ilstrup DM
        Treating bulimia with desipramine: A double-blind, placebo-controlled study.
        Arch Gen Psychiatry. 1986; 43: 182-186
        • Katz JL
        • Kuperberg A
        • Pollack CP
        • Walsh BT
        • Zumoff B
        • Weiner H
        Is there a relationship between eating disorder and affective disorder? New evidence from sleep recordings.
        Am J Psychiatry. 1984; 141: 753-759
        • Kupfer DJ
        • Foster F
        • Reich L
        • Thompson K
        • Weiss B
        EEG sleep changes as predictors in depression.
        Am J Psychiatry. 1976; 138: 429-434
        • Kupfer DJ
        • Spiker DG
        • Coble PA
        • McPartland RJ
        • Ulrich R
        The application of EEG sleep for the differential diagnosis of affective disorders.
        Am J Psychiatry. 1978; 135: 69-74
        • Kupfer DJ
        • Ulrich RF
        • Coble PA
        • Jarrett DB
        • Grochocinski VJ
        • Doman J
        • Matthews G
        • Borbely A
        EEG sleep of younger depressives: Comparison to normals.
        Arch Gen Psychiatry. 1985; 42: 806-810
        • Kupfer DJ
        • Reynolds CF
        • Ulrich RF
        • Grochocinski VJ
        Comparison of automated REM and slow-wave sleep analysis in young and middle-aged depressed subjects.
        Biol Psychiatry. 1986; 21: 189-200
        • Lahmeyer HW
        • Poznanski EO
        • Bellur SN
        EEG sleep in depressed adolescents.
        Am J Psychiatry. 1983; 140: 1150-1153
        • Levy AB
        • Dixon KN
        • Schmidt HS
        Sleep architecture in eating disorder patients.
        in: Presented at the American Psychiatric Association Annual Meeting, May 12, 19861986
        • Liebowitz MR
        • Quitkin FM
        • Stewart JW
        • McGrath PJ
        • Harrison W
        • Rabkin J
        • Tricamo E
        • Markowitz JS
        • Klein DF
        Phenelzine v imipramine in atypical depression: A preliminary report.
        Arch Gen Psychiatry. 1984; 41: 669-677
        • Lindy DC
        • Walsh BT
        • Roose SP
        • Gladis M
        • Glassman AH
        The Dexamethasone Suppression Test in bulimia.
        Am J Psychiatry. 1985; 142: 1375-1376
        • Mitchell JE
        • Groat R
        A placebo-controlled, double-blind trial of amitriptyline in bulimia.
        J Clin Psychopharmacol. 1984; 4: 186-193
        • Mitchell JE
        • Pyle RL
        • Hatsukami D
        • Boutzcoff LI
        The Dexamethasone Suppression Test in patients with bulimia.
        J Clin Psychiatry. 1985; 45: 508-511
        • Pope Jr, HG
        • Hudson JI
        Antidepressant drug therapy for bulimia: Current status.
        J Clin Psychiatry. 1986; 47: 339-345
        • Pope Jr, HG
        • Hudson JI
        • Jonas JM
        • Yurgelun-Todd D
        Bulimia treated with imipramine: A placebo-controlled double-blind study.
        Am J Psychiatry. 1983; 140: 554-558
        • Puig-Antich J
        • Goetz R
        • Hanlon C
        • Davies M
        • Thompson J
        • Chambers WJ
        • Tabrizi MA
        • Weitzman ED
        Sleep architecture and REM sleep measures in prepubertal children with major depression.
        Arch Gen Psychiatry. 1982; 39: 932-939
        • Reynolds CF
        • Newton TF
        • Shaw DH
        • Coble PA
        • Kupfer DJ
        Electroencephalographic sleep findings in outpatients with primary depression.
        Psychiatry Res. 1982; 6: 65-72
        • Robins LN
        • Heizer JI
        • Croughan J
        • Williams J
        • Spitzer RL
        NIMH Diagnostic Interview Schedule.
        2nd ed. National Institute of Mental Health, Rockville, MD1980
        • Rush AJ
        • Giles DE
        • Roffwarg HP
        • Parker CR
        Sleep EEG and Dexamethasone Suppression Test findings in outpatients with unipolar major depressive disorder.
        Biol Psychiatry. 1982; 17: 327-341
        • Society of Actuaries and Associates of Life Insurance Medical Directors of America
        1979 Build Study.
        1980 (Chicago.)
        • Spitzer R
        • Endicott J
        • Robins E
        Research Diagnostic Criteria.
        Arch Gen Psychiatry. 1978; 34: 773-782
        • Taska LS
        • Kupfer DJ
        Sleep Scoring Manual. Western Psychiatric Institute and Clinic, Pittsburgh1982
        • Taub JM
        • Hawkins DR
        • Ban de Castle RL
        Electrographic analysis of the sleep cycle in young depressed patients.
        Biol Psychol. 1978; 7: 203-214
        • Walsh BT
        • Stewart JW
        • Roose SP
        • Gladis M
        • Glassman AH
        Treatment of bulimia with phenelzine: A double-blind, placebo-controlled study.
        Arch Gen Psychiatry. 1984; 41: 1105-1109
        • Walsh BT
        • Goetz R
        • Roose SP
        • Fingeroth S
        • Glassman AH
        EEG-monitored sleep in anorexia nervosa and bulimia.
        Biol Psychiatry. 1985; 20: 947-956
        • Walsh BT
        • Roose SP
        • Glassman AH
        • Gladis M
        • Sadik C
        Bulimia and depression.
        Psychosom Med. 1985; 47: 123-131
        • Weilberg JB
        • Stakes JW
        • Brotman A
        • Herzog DB
        Sleep architecture in bulimia: A pilot study.
        Biol Psychiatry. 1985; 20: 225-228