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Abstract
Acetylcholinesterase (AChE)from erythrocytes was solubilized by Triton X-100. Size
and charge heterogeneity of AChE was investigated by polyacrylamide gel electrophoresis
(PAGE) and isoelectric focusing (IEF) in polyacrylamide gels in the presence of 0.5%
(v/v) Triton X-100. There were no interindividual differences in these parameters
in 46 psychiatric patients (schizophrenia, major affective disorder, personality disorder,
dependency, dementia) and controls. The specific activity of solubilized AChE did
not discriminate between controls and patients or between the diagnostic subgroups.
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Article info
Publication history
Received in revised form:
September 30,
1986
Received:
July 31,
1986
Identification
Copyright
© 1987 Published by Elsevier Inc.