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Abstract
Electroencephalogram (EEG) coherence (COH) and power measures were included in a series
of stepwise discriminant analyses to determine which variables were most sensitive
in the differentiation of four psychiatric inpatient groups and two major classes
of psychotropic medication. Eight channels of eyes-closed, bipolar EEG activity were
recorded from 74 inpatients (paranoid schizophrenics, dysthymics, major affectives
receiving tricyclics, neuroleptics, or no medication, and geriatrics). Discriminant
analyses were conducted for theta, alpha, and fast beta frequency bands for power
variables, COH variables, and the resultant significant power and COH discriminating
variables. Without exception, COH measures, usually in the alpha band, were more sensitive
than power measures in differentiating the various groups. Results suggested that
COH decreases with age, is greatest in paranoid schizophrenics, decreases with neuroleptic
medication, and increases with tricyclic antidepressants. Group differences were interpreted
in accordance with an arousal model for COH.
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Article info
Publication history
Received in revised form:
March 10,
1986
Received:
January 14,
1986
The authors wish to acknowledge the significant contributions and assistance of Cornelis Boelhouwer M.D., and Michael Molyn M.A.Footnotes
☆Portions of this work were presented at the 138th Annual Meeting of the APA, Dallas, TX, May 1985.
Identification
Copyright
© 1986 Published by Elsevier Inc.
