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Research Article| Volume 21, ISSUE 2, P170-176, February 1986

EEG observations during combined haloperidol-lithium treatment

  • R.O. Addy
    Correspondence
    Address reprint requests to Dr.R.O. Addy, Department of Psychiatry, Cleveland Metropolitan General Hospital, 3395 Scranton Road, Cleveland, OH 44109.
    Affiliations
    From the Case Western Reserve University School of Medicine and the Cleveland Metropolitan General/Highland View Hospital, Cleveland, OH USA
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  • Roland H. Foliart
    Affiliations
    From the Case Western Reserve University School of Medicine and the Cleveland Metropolitan General/Highland View Hospital, Cleveland, OH USA
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  • Avtar S. Saran
    Affiliations
    From the Case Western Reserve University School of Medicine and the Cleveland Metropolitan General/Highland View Hospital, Cleveland, OH USA
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  • Daniel S.P. Schubert
    Affiliations
    From the Case Western Reserve University School of Medicine and the Cleveland Metropolitan General/Highland View Hospital, Cleveland, OH USA
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      Abstract

      Some reports have indicated a neurotoxic interaction of haloperidol and lithium, whereas others have not found this interaction. This is a report on two patients who showed both photomyoclonic and photoparoxysmal responses while on combined lithium-haloperidol treatment. We suggest that these findings, which have not been previously reported to be associated with combined lithium-haloperidol treatment, reflect neurotoxicity and that electroencephalogram (EEG) monitoring should be done on patients receiving this combined medication regimen.
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