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Research Article| Volume 20, ISSUE 11, P1149-1155, November 1985

Democlocycline improves hyponatremia in chronic schizophrenics

  • Morris B. Goldman
    Correspondence
    Address reprint requests to Dr. Morris B. Goldman, Department of Psychiatry, Box 411, University of Chicago Medical Center, 5841 South Maryland Avenue, Chicago, IL, USA
    Affiliations
    From the Department of Psychiatry, University of Chicago Medical Center, Chicago, IL, USA
    Search for articles by this author
  • Daniel J. Luchins
    Affiliations
    From the Department of Psychiatry, University of Chicago Medical Center, Chicago, IL, USA
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DOI:https://doi.org/10.1016/0006-3223(85)90172-6
Democlocycline improves hyponatremia in chronic schizophrenics
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      Abstract

      Serum sodium concentration increased significantly in eight hyponatremic schizophrenic subjects treated with demeclocycline. The incidence of severe hyponatremic episodes was significantly reduced. The authors argue that mild impairments in urinary dilution contribute to water intoxication in most chronic psychotics who develop this syndrome. Demeclocycline may help these patients.
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      Article info

      Publication history

      Received in revised form: May 6, 1985
      Received: February 23, 1985

      Identification

      DOI: https://doi.org/10.1016/0006-3223(85)90172-6

      Copyright

      © 1985 Published by Elsevier Inc.

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