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A brief summary of the articles appearing in this issue of Biological Psychiatry
Telomere length has been used as a marker of cellular aging. Wikgren et al. (pages 294–300) investigated leukocyte telomere length and hypothalamic-pituitary-adrenal (HPA) axis measurements in patient...
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279
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| Commentaries |
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Child Abuse and Psychiatric Illness
Child abuse is a nonspecific risk factor associated with an increased risk for a range of psychiatric and substance use disorders. The paper in this issue by Dannlowski et al. () adds to a growing bod...
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Joan Kaufman
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280-281
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Low Cortisol and Risk and Resilience to Stress-Related Psychiatric Disorders
A number of both preclinical and clinical studies have investigated the long-term effects of exposure to stressful or traumatic life events on the regulation of the stress hormone system. In this issu...
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Elisabeth B. Binder,
Florian Holsboer
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282-283
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Memory Reconsolidation Processes and Posttraumatic Stress Disorder: Promises and Challenges of Translational Research
During the past decade, there was a vigorous renewal of interest in postretrieval memory processes. Numerous studies using a variety of species and learning paradigms, and targeting various brain circ...
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Jacek De̢biec
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284-285
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| Priority Communication |
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Limbic Scars: Long-Term Consequences of Childhood Maltreatment Revealed by Functional and Structural Magnetic Resonance Imaging
24 November 2011
Background: Childhood maltreatment represents a strong risk factor for the development of depression and posttraumatic stress disorder (PTSD) in later life. In the present study, we investigated the n...
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Udo Dannlowski,
Anja Stuhrmann,
Victoria Beutelmann,
Peter Zwanzger,
Thomas Lenzen,
Dominik Grotegerd,
Katharina Domschke,
Christa Hohoff,
Patricia Ohrmann,
Jochen Bauer,
Christian Lindner,
Christian Postert,
Carsten Konrad,
Volker Arolt,
Walter Heindel,
Thomas Suslow,
Harald Kugel
et al.
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286-293
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| Archival Reports |
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Short Telomeres in Depression and the General Population Are Associated with a Hypocortisolemic State
07 November 2011
Background: The hypothalamic-pituitary-adrenal (HPA) axis plays a central role in stress regulation, and leukocyte telomere length (TL) has been suggested to represent a cumulative measure of stress. ...
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Mikael Wikgren,
Martin Maripuu,
Thomas Karlsson,
Katarina Nordfjäll,
Jan Bergdahl,
Johan Hultdin,
Jurgen Del-Favero,
Göran Roos,
Lars-Göran Nilsson,
Rolf Adolfsson,
Karl-Fredrik Norrback
et al.
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294-300
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Reorganization of Synaptic Inputs to the Hypothalamic Paraventricular Nucleus During Chronic Psychogenic Stress in Rats
05 December 2011
Background: Chronic stress in humans precipitates hyper-reactivity of the hypothalamic-pituitary-adrenocortical (HPA) axis and triggers symptoms associated with certain forms of depression. Reorganiza...
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Ildikó H. Miklós,
Krisztina J. Kovács
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301-308
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Glucocorticoid Receptor Pathway Components Predict Posttraumatic Stress Disorder Symptom Development: A Prospective Study
05 December 2011
Background: Biological correlates of posttraumatic stress disorder (PTSD) have mostly been studied using cross-sectional or posttrauma prospective designs. Therefore, it remains largely unknown whethe...
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Mirjam van Zuiden,
Elbert Geuze,
Hanneke L.D.M. Willemen,
Eric Vermetten,
Mirjam Maas,
Karima Amarouchi,
Annemieke Kavelaars,
Cobi J. Heijnen
et al.
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309-316
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Site-Specific Genetic Manipulation of Amygdala Corticotropin-Releasing Factor Reveals Its Imperative Role in Mediating Behavioral Response to Challenge
25 July 2011
Background: Faulty regulation of the central extrahypothalamic corticotropin-releasing factor (CRF) expression is associated with stress-related psychopathologies including anxiety disorders and depre...
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Limor Regev,
Michael Tsoory,
Shosh Gil,
Alon Chen
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317-326
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Catecholamines in the Bed Nucleus of the Stria Terminalis Reciprocally Respond to Reward and Aversion
24 November 2011
Background: Traditionally, norepinephrine has been associated with stress responses, whereas dopamine has been associated with reward. Both of these catecholamines are found within the bed nucleus of ...
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Jinwoo Park,
Robert A. Wheeler,
Khristy Fontillas,
Richard B. Keithley,
Regina M. Carelli,
R. Mark Wightman
et al.
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327-334
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Concussive Brain Injury Enhances Fear Learning and Excitatory Processes in the Amygdala
12 December 2011
Background: Mild traumatic brain injury (cerebral concussion) results in cognitive and emotional dysfunction. These injuries are a significant risk factor for the development of anxiety disorders, inc...
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Maxine L. Reger,
Andrew M. Poulos,
Floyd Buen,
Christopher C. Giza,
David A. Hovda,
Michael S. Fanselow
et al.
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335-343
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Lifetime Adversity Leads to Blunted Stress Axis Reactivity: Studies from the Oklahoma Family Health Patterns Project
24 November 2011
Background: Can stressful events in early life alter the response characteristics of the human stress axis? Individual differences in stress reactivity are considered potentially important in long-ter...
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William R. Lovallo,
Noha H. Farag,
Kristen H. Sorocco,
Andrew J. Cohoon,
Andrea S. Vincent
et al.
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344-349
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Child Abuse and Neglect, MAOA, and Mental Health Outcomes: A Prospective Examination
28 October 2011
Background: Studies have examined the interaction of MAOA genotype with childhood maltreatment in relation to depressive symptomatology and alcohol abuse with conflicting findings. Both high- and low-...
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Valentina Nikulina,
Cathy Spatz Widom,
Linda M. Brzustowicz
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350-357
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Gene Profiling Reveals a Role for Stress Hormones in the Molecular and Behavioral Response to Food Restriction
22 August 2011
Background: Food restriction is known to enhance learning and motivation. The neural mechanisms underlying these responses likely involve alterations in gene expression in brain regions mediating the ...
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Douglas J. Guarnieri,
Catherine E. Brayton,
Sarah M. Richards,
Jaime Maldonado-Aviles,
Joseph R. Trinko,
Jessica Nelson,
Jane R. Taylor,
Shannon L. Gourley,
Ralph J. DiLeone
et al.
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358-365
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Cognitive-Behavioral Stress Management Reverses Anxiety-Related Leukocyte Transcriptional Dynamics
17 November 2011
Background: Chronic threat and anxiety are associated with pro-inflammatory transcriptional profiles in circulating leukocytes, but the causal direction of that relationship has not been established. ...
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Michael H. Antoni,
Susan K. Lutgendorf,
Bonnie Blomberg,
Charles S. Carver,
Suzanne Lechner,
Alain Diaz,
Jamie Stagl,
Jesusa M.G. Arevalo,
Steven W. Cole
et al.
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366-372
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Variations in the Promoter Region of the Serotonin Transporter Gene and Biased Attention for Emotional Information: A Meta-Analysis
06 December 2011
Background: Selective attention to negative information has been strongly implicated in the etiology and maintenance of anxiety and offered as a potential intermediate phenotype for anxiety disorders....
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Lee Pergamin-Hight,
Marian J. Bakermans-Kranenburg,
Marinus H. van IJzendoorn,
Yair Bar-Haim
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373-379
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Neural Signature of Reconsolidation Impairments by Propranolol in Humans
02 December 2011
Background: The retrieval of consolidated memories may result in their destabilization, requiring a restabilization process called reconsolidation. During reconsolidation, memories become sensitive to...
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Lars Schwabe,
Karim Nader,
Oliver T. Wolf,
Thomas Beaudry,
Jens C. Pruessner
et al.
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380-386
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Erratum to: The Prevention of Recurrent Episodes of Depression with Venlafaxine for Two Years (PREVENT) Study: Outcomes from the Acute and Continuation Phases
It has been discovered that the patient flowchart was not included in Supplement 2 for “The Prevention of Recurrent Episodes of Depression with Venlafaxine for Two Years (PREVENT) Study: Outcomes from...
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387
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Erratum to: Catechol-O-Methyltransferase Val158Met Polymorphism Moderates Anterior Cingulate Volume in Posttraumatic Stress Disorder
Errors have been discovered in “Catechol-O-Methyltransferase Val158Met Polymorphism Moderates Anterior Cingulate Volume in Posttraumatic Stress Disorder” by Schulz-Heik et al., published in Biological...
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388
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Ifenprodil for the Treatment of Flashbacks in Female Posttraumatic Stress Disorder Patients with a History of Childhood Sexual Abuse
10 November 2011
A recent meta-analysis showed that a history of sexual abuse is associated with increased risk for a lifetime diagnosis of multiple psychiatric disorders, such as posttraumatic stress disorder (PTSD),...
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Akira Kishimoto,
Motonori Kaneko,
Yurie Gotoh,
Kenji Hashimoto
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e7-e8
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Clinical and Cerebral Volumetric Effects of Sodium Benzoate, a d-Amino Acid Oxidase Inhibitor, in a Drug-Naïve Patient with Major Depression
16 December 2011
Sodium benzoate, an inhibitor of d-amino acid oxidase (DAO), can prevent degradation of d-amino acid (DAA) and might be helpful for the relief of anxiety or depression symptoms (). Its therapeutic rol...
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Chien-Han Lai,
Hsien-Yuan Lane,
Guochuan Emil Tsai
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e9-e10
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| Frontmatter |
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Editorial Board
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A1
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Subscribers Page
Biological Psychiatry (ISSN 0006-3223) is published semimonthly by Elsevier Inc., 360 Park Avenue South, New York, NY 10010-1710. Periodicals postage paid at New York, NY and additional mailing office...
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A2
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Table of Contents
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A3-A4
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Guide for Authors
Biological Psychiatry is the official journal of the Society of Biological Psychiatry. The Journal rapidly publishes reports of novel results on a broad range of topics related to the pathophysiology ...
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A5-A6
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Manuscript Submission Form
This form should be completed by every author and accompany every new manuscript submission. It must be fully complete and accurate, with signatures from ALL authors, before a manuscript can be finali...
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A7
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