Biological Psychiatry
Volume 71, Issue 8 , Pages 714-724 , 15 April 2012

β-Arrestin2 Regulates Cannabinoid CB1 Receptor Signaling and Adaptation in a Central Nervous System Region–Dependent Manner

  • Peter T. Nguyen

      Affiliations

    • Department of Pharmacology and Toxicology and Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, Virginia
  • ,
  • Cullen L. Schmid

      Affiliations

    • Departments of Molecular Therapeutics and Neuroscience, The Scripps Research Institute, Jupiter, Florida
  • ,
  • Kirsten M. Raehal

      Affiliations

    • Departments of Molecular Therapeutics and Neuroscience, The Scripps Research Institute, Jupiter, Florida
  • ,
  • Dana E. Selley

      Affiliations

    • Department of Pharmacology and Toxicology and Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, Virginia
  • ,
  • Laura M. Bohn

      Affiliations

    • Departments of Molecular Therapeutics and Neuroscience, The Scripps Research Institute, Jupiter, Florida
  • ,
  • Laura J. Sim-Selley

      Affiliations

    • Department of Pharmacology and Toxicology and Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, Virginia
    • Corresponding Author InformationAddress correspondence to Laura J. Sim-Selley, Ph.D., Box 980524, 1112 E. Clay Street, Richmond, VA 23298

Received 4 August 2011 ,Revised 25 October 2011 ,Accepted 30 November 2011.

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PII: S0006-3223(11)01200-5

doi: 10.1016/j.biopsych.2011.11.027

Biological Psychiatry
Volume 71, Issue 8 , Pages 714-724 , 15 April 2012