Biological Psychiatry
Volume 67, Issue 9 , Pages 880-886, 1 May 2010

Ghrelin Increases the Rewarding Value of High-Fat Diet in an Orexin-Dependent Manner

  • Mario Perello

      Affiliations

    • Department of Internal Medicine (Divisions of Hypothalamic Research and Endocrinology & Metabolism), The University of Texas Southwestern Medical Center, Dallas, Texas
    • ,
  • Ichiro Sakata

      Affiliations

    • Department of Internal Medicine (Divisions of Hypothalamic Research and Endocrinology & Metabolism), The University of Texas Southwestern Medical Center, Dallas, Texas
    • ,
  • Shari Birnbaum

      Affiliations

    • Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas
    • ,
  • Jen-Chieh Chuang

      Affiliations

    • Department of Internal Medicine (Divisions of Hypothalamic Research and Endocrinology & Metabolism), The University of Texas Southwestern Medical Center, Dallas, Texas
    • ,
  • Sherri Osborne-Lawrence

      Affiliations

    • Department of Internal Medicine (Divisions of Hypothalamic Research and Endocrinology & Metabolism), The University of Texas Southwestern Medical Center, Dallas, Texas
    • ,
  • Sherry A. Rovinsky

      Affiliations

    • Department of Internal Medicine (Divisions of Hypothalamic Research and Endocrinology & Metabolism), The University of Texas Southwestern Medical Center, Dallas, Texas
    • ,
  • Jakub Woloszyn

      Affiliations

    • Department of Internal Medicine (Divisions of Hypothalamic Research and Endocrinology & Metabolism), The University of Texas Southwestern Medical Center, Dallas, Texas
    • ,
  • Masashi Yanagisawa

      Affiliations

    • Department of Molecular Genetics and Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, Texas
    • ,
  • Michael Lutter

      Affiliations

    • Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas
    • ,
  • Jeffrey M. Zigman

      Affiliations

    • Department of Internal Medicine (Divisions of Hypothalamic Research and Endocrinology & Metabolism), The University of Texas Southwestern Medical Center, Dallas, Texas
    • Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, Texas
    • Corresponding Author InformationAddress correspondence to Jeffrey M. Zigman, M.D., Ph.D., The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, MC 9077, Dallas, TX 75390-9077

Received 12 May 2009; received in revised form 25 September 2009; accepted 23 October 2009. published online 25 December 2009.

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 Authors ML and JMZ contributed equally to this work.

PII: S0006-3223(09)01318-3

doi:10.1016/j.biopsych.2009.10.030

Biological Psychiatry
Volume 67, Issue 9 , Pages 880-886, 1 May 2010

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