Biological Psychiatry
Volume 67, Issue 2 , Pages 110-116 , 15 January 2010

Nucleus Accumbens Deep Brain Stimulation Decreases Ratings of Depression and Anxiety in Treatment-Resistant Depression

  • Bettina H. Bewernick

      Affiliations

    • Department of Psychiatry and Psychotherapy, University Hospital, Bonn, Germany
    • ,
  • René Hurlemann

      Affiliations

    • Department of Psychiatry and Psychotherapy, University Hospital, Bonn, Germany
    • ,
  • Andreas Matusch

      Affiliations

    • Department of Psychiatry and Psychotherapy, University Hospital, Bonn, Germany
    • ,
  • Sarah Kayser

      Affiliations

    • Department of Psychiatry and Psychotherapy, University Hospital, Bonn, Germany
    • ,
  • Christiane Grubert

      Affiliations

    • Department of Psychiatry and Psychotherapy, University Hospital, Bonn, Germany
    • ,
  • Barbara Hadrysiewicz

      Affiliations

    • Department of Psychiatry and Psychotherapy, University Hospital, Bonn, Germany
    • ,
  • Nikolai Axmacher

      Affiliations

    • Department of Psychiatry and Psychotherapy, University Hospital, Bonn, Germany
    • Department of Epileptology, University Hospital, Bonn, Germany
    • ,
  • Matthias Lemke

      Affiliations

    • Department of Psychiatry, Hospital Alsterdorf, Hamburg, Germany
    • ,
  • Deirdre Cooper-Mahkorn

      Affiliations

    • Department of Psychiatry and Psychotherapy, University Hospital, Bonn, Germany
    • ,
  • Michael X. Cohen

      Affiliations

    • Department of Psychology, University of California, Davis, California
    • ,
  • Holger Brockmann

      Affiliations

    • Department of Nuclear Medicine, University Hospital, Bonn, Germany
    • ,
  • Doris Lenartz

      Affiliations

    • Department of Functional Neurosurgery, University Hospital, Cologne, Germany
    • ,
  • Volker Sturm

      Affiliations

    • Department of Functional Neurosurgery, University Hospital, Cologne, Germany
    • ,
  • Thomas E. Schlaepfer

      Affiliations

    • Department of Psychiatry and Psychotherapy, University Hospital, Bonn, Germany
    • Departments of Psychiatry and Mental Health, The Johns Hopkins University, Baltimore, Maryland
    • Corresponding Author InformationAddress correspondence to Thomas E. Schlaepfer, M.D., Department of Psychiatry, University Hospital, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany

Received 9 July 2009 ,Revised 3 September 2009 ,Accepted 11 September 2009.

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PII: S0006-3223(09)01094-4

doi: 10.1016/j.biopsych.2009.09.013

Biological Psychiatry
Volume 67, Issue 2 , Pages 110-116 , 15 January 2010

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