Biological Psychiatry
Volume 67, Issue 3 , Pages 275-278 , 1 February 2010

Dopamine Type 2/3 Receptor Availability in the Striatum and Social Status in Human Volunteers

  • Diana Martinez

      Affiliations

    • Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York
    • Corresponding Author InformationAddress correspondence to Diana Martinez, M.D., New York State Psychiatric Institute, 1051 Riverside Drive, Box #31, New York, NY 10032
  • ,
  • Daria Orlowska

      Affiliations

    • Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York
  • ,
  • Rajesh Narendran

      Affiliations

    • Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania
  • ,
  • Mark Slifstein

      Affiliations

    • Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York
  • ,
  • Fei Liu

      Affiliations

    • Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York
  • ,
  • Dileep Kumar

      Affiliations

    • Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York
  • ,
  • Allegra Broft

      Affiliations

    • Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York
  • ,
  • Ronald Van Heertum

      Affiliations

    • Department of Radiology, Columbia University, College of Physicians and Surgeons, New York, New York
  • ,
  • Herbert D. Kleber

      Affiliations

    • Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York

Received 18 December 2008 ,Revised 23 July 2009 ,Accepted 28 July 2009.

  • Image Result

    Correlation between [11C]raclopride BP (x axis) and social status, measured with the Barratt Simplified Measure of Social Status (BSMSS). A positive correlation was seen, where higher BP correlated wi

    Correlation between [11C]raclopride BP (x axis) and social status, measured with the Barratt Simplified Measure of Social Status (BSMSS). A positive correlation was seen, where higher BP correlated with higher BSMSS (r = .71, p = .004, age-corrected p = .007). BP, binding potential.

  • Image Result
    Correlation between [11C]raclopride BP (x axis) and score on the Multidimensional Scale of Perceived Social Support (MSPSS). A positive correlation was seen, where higher BP correlated with higher sco

    Correlation between [11C]raclopride BP (x axis) and score on the Multidimensional Scale of Perceived Social Support (MSPSS). A positive correlation was seen, where higher BP correlated with higher score on the MSPSS (r = .73, p = .005, age-corrected p = .02). BP, binding potential.

PII: S0006-3223(09)00965-2

doi: 10.1016/j.biopsych.2009.07.037

Biological Psychiatry
Volume 67, Issue 3 , Pages 275-278 , 1 February 2010